张湛曰:夫经方之难精,由来尚已。今病有内同而外异,亦有内异而外同,故五脏六腑之盈虚,血脉荣卫之通塞,固非耳目之所察,必先诊候以审之。而寸口关尺,有浮沉弦紧之乱;俞穴流注,有高下浅深之差;肌肤筋骨,有厚薄刚柔之异。唯用心精微者,始可与言于兹矣。今以至精至微之事,求之于至粗至浅之思,岂不殆哉?若盈而益之,虚而损之,通而彻之,塞而壅之,寒而冷之,热而温之,是重加其疾,而望其生,吾见其死矣。故医方卜筮,艺能之难精者也。既非神授,何以得其幽微?世有愚者,读方三年,便谓天下无病可治,及治病三年,乃知天下无方可用。故学者必须博极医源,精勤不倦,不得道听途说,而言医道已了,深自误哉!
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